BioNTech to present interim Phase I/II date for mRNA vaccine at AACR

Mainz, Germany, March 7, 2017 – BioNTech AG, a fully-integrated biotechnology company pioneering individualized cancer immunotherapy, today announced that it will present interim data from an ongoing Phase I/II clinical trial of its Lipo-MERIT vaccine in patients with malignant melanoma at the 2017 Annual Meeting of the American Association for Cancer Research (AACR), taking place April 1 – 5 in Washington, DC. This is the first example of a clinically applied systemic mRNA-based cancer immunotherapy.

Permanent Abstract Number: CT034
Poster: “A First-in-Human Phase I/II Clinical Trial Assessing Novel mRNA-lipoplex Nanoparticles for Potent Melanoma Immunotherapy”
Date: Monday, April 3, 2017
Session: PO.CT01 – Phase I Clinical Trials in Progress
Time: 8:00AM – 12:00PM Eastern Daylight Time
Location: Poster Section 33

The Phase I/II dose escalation Lipo-MERIT trial (NCT02410733) in melanoma patients assesses the safety and tolerability as well as the potency of inducing antigen-specific immune responses of the first systemic mRNA vaccine to be developed based on BioNTech’s mRNA nanoparticle immunotherapy platform.

*** Announcement in Englisch – PDF ***